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Disease-modifying treatments for multiple sclerosis - a review of approved medications

Patients with Crohns disease are usually under increased oxidative stress and have lower levels of antioxidant vitamins

In this essay, we shall look at what came before and the journey after 1912 (Figure 2) through clinical associations, recognition of the role of copper, the disease genetics, therapeutic developments, and eventually, the cloning of the gene harboring mutations, which led to mutation analysis and an increased understanding of the cellular mechanisms involved in copper metabolism

Available online at: (Accessed December 29, 2025)

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