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doi:10.1136/bmj.r1512 Chen, J., Siliceo, S.L., Ni, Y., Nielsen, H.B., Xu, A., & Panagiotou, G

For more than two decades, researchers pursued the goal of delivering GLP-1 receptor activation through an oral tablet, a pursuit complicated by the fundamental biochemistry of peptide drugs: their vulnerability to acid hydrolysis in the stomach, enzymatic degradation in the gastrointestinal tract, and poor absorption across the intestinal epithelium

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Extensive research over the past decade has provided evidence that GLP-1 receptor agonists do not appear to increase the risk of pancreatic cancer

No studies of metformin pharmacokinetic parameters according to race have been performed