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*The absolute risk is still very low (e.g., 1 in 10,000 per year as per regulators)

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Fatal and non-fatal cardiovascular events in a general population prescribed sibutramine in New Zealand: a prospective cohort study

MT-II is investigated as a melanocortin receptor agonist (primarily MC1R/MC4R ) for studies spanning melanogenesis , UV/photobiology , energy balance , and neuroendocrine signaling