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TSPO ligands have been used as markers of neuroinflammation and microglial activity in positron emission tomography (PET) imaging

Boyd SD, Ullrich MS, Skopp A, Winkler DD

Its cyclic structure formed via a lactam bridge between lysine and aspartate residues confers substantially greater metabolic stability than native -MSH and the linear Melanotan 1 analogue, and produces a distinct, broad-spectrum receptor activity profile

Esto puede tener una influencia importante en nuestro enfoque futuro sobre el tratamiento de la obesidad, dice Signe Soerensen Torekov

After 21 days, mice were randomized into four different experimental treatment groups: vehicle, cisplatin (4 mg kg 1 once per week for 1 week), RSL3 (50 mg kg 1 , two times per week for 2 weeks) and cisplatin in combination with RSL3