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Serotonin- and dopamine-related gene expression in db/db mice islets and in MIN6 -cells treated with palmitate and oleate

[PMC free article: PMC5699929] [PubMed: 28555362] (A prospective, population based registry of cases of drug induced liver injury occurring in Delaware during 2014, identified 20 cases [2.7 per 100,000] overall, including 6 due to HDS products, all of which were proprietary multiingredient supplements, but none were Hydroxycut products)

Oxidative stress is a mainstay pathophysiological mechanism of cerebral injury, which occurs due to the over-liberation of reactive oxygen species (ROS), resulting in an imbalance of oxidant-antioxidant equilibrium in favour of oxidation, and consequently, mitochondrial dysfunction occurs

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