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Sunken cheeks, sagging skin, more visible fine lines and wrinkles can become more pronounced, especially if you are over 40

Use caution if you have liver or kidney disease, bipolar disorder, seizure disorders, or if you take medications that affect methylation or neurotransmitters

Highdose vitamin C infusions are sometimes used as adjunct therapy in cancer treatment or to combat infections, but they may become prooxidative at very high concentrations and should only be administered by qualified professionals