What are the recommendations for a patient with a Body Mass Index (BMI) less than 22 who is taking Glucagon-Like Peptide-1 (GLP-1) receptor agonists, such as semaglutide (GLP-1 receptor agonist) or tirzepatide (GLP-1 and glucose-dependent insulinotropic polypeptide receptor agonist), for weight loss?
& Alan, G
J Gen Intern Med 24(1):129131 Kamata Y, Takano K, Kishihara E, Watanabe M, Ichikawa R, Shichiri M (2017) Distinct clinical characteristics and therapeutic modalities for diabetic ketoacidosis in type 1 and type 2 diabetes mellitus
To date, conventional Na + or H + ion coupling has yet to be observed in OCTs or OATs, with OCTs thought to function as uniporters rather than symporters, and the OATs coupling the uphill transport of organic anions to the downhill movement of intracellular organic anions, such as -ketoglutarate 25
FDAs strict view in the Purolea case that AI enrichment does not replace validation suggests that any AI implementation must be documented in protocols or SOPs, with evidence of testing and review archived in the quality system
