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It is a substrate for PARPs (poly (ADP-ribose) polymerases) (repair of damaged DNA) and is important to prevent neurodegenerative processes

In this model, D-cycloserine (DCS), a partial agonist at the glycine co-agonist site on the NMDA receptor (see Figure 4), decreased compulsive lever-pressing (Albelda, Bar-On, & Joel, 2010)

Hasanein P, Ghafari-Vahed M, Khodadadi I

Recent enzymatic analyses in lymphocytes showed that BD patients in the depressive phase had lower levels of mitochondrial complex II activity compared to those in the euthymic phase, with a significant negative correlation between the Hamilton Depression Rating Scale score and mitochondrial complex II activity [50], providing a strong link between reduced mitochondrial function and current bipolar depressive phase

Joensuu M, Lanoue V, Hotulainen P