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Their presence in these regions is not incidental

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Clinical Trials on Dual GLP-1/GIP Agonists Tirzepatide: Combining GLP-1 and GIP for Enhanced Weight Loss Tirzepatide is a dual glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist developed to enhance weight loss beyond that achieved with GLP-1 receptor agonist monotherapy

The decision to adjust dose based on heart rate should involve the overall clinical picture, not just one number in isolation

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