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Injections Most animal studies use subcutaneous or intramuscular injections

Of course there are, and many of them are on Substack

[1:08:58] I started dialing down how much I do because of that, and now it's limited to a handful of things

Topically, it is noncytotoxic to melanocytes, and it does not promote changes in serum thyroid stimulating hormone (TSH) levels [65]

however, some individuals may experience mild skin sensitivity depending on: Formulation concentration Skin type Frequency of cosmetic application Concurrent cosmetic ingredients Possible Cosmetic Reactions Mild redness Temporary tingling sensations Skin irritation Dryness Increased skin sensitivity Temporary blue discoloration when higher concentrations are utilized Higher concentrations are not always preferred and may increase the likelihood of cosmetic skin irritation, particularly in sensitive-skin formulations