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We evaluated pain behaviors and analyzed dorsal root ganglia (DRG) for markers of oxidative stress, mitochondrial respiratory chain complexes, fission (DRP1) and fusion (OPA1) proteins, and mitochondrial morphology/ultrastructure

The antiepileptic regimen was optimized to sustained-release valproic acid (500 mg twice daily), with therapeutic serum levels maintained

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(2) a composite incidence of MACE (HR 0.95