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The survival of T-ALL cells after DOX treatment was correlated with the expression of Mitofusin-2 (MFN-2)A GTPase protein that mediates mitochondrial fusionWith an increase in the expression of CTE complexes as well as a proportional increase in oxygen consumption rate (OCR), and increased sensitivity to DOX was evident upon inactivating MFN-2 by CRISPR (Decker et al., 2020)

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Moreover, in contrast to tap or distilled water, there are no chemicals, salts, ions, preservatives, or additives in SWFI

The current public schedule is: TRIUMPH-1: general obesity, 80-week treatment duration, the largest TRIUMPH trial, pivotal for the NDA filing