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Future research should incorporate female animal models to investigate potential sex-specific responses to MAOB inhibition, which will be essential for fully understanding the translational implications of astrocytic GABA dysregulation in PTSD across sexes

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Under pathological conditions, long-term excessive stress can cause damage to the endoplasmic reticulum function, and endoplasmic reticulum stress activates the apoptosis pathway, which leads to nerve cell damage and even death (Xuan et al., 2020)

P-values were determined with a two-sample paired t- test, with significance cut off value set to p = 0.05