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In a randomized, placebo-controlled intervention study with more than 900 older participants experiencing psychological distress, daily supplementation with folic acid (400 g) and vitamin B 12 (100 g) for two years did not reduce the occurrence of symptoms of depression despite significantly improving blood folate, vitamin B 12 , and homocysteine levels compared to placebo (109)

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Study product was administered in a skinfold in the abdomen using a NovoPen 4 by qualified site staff delegated to this task at the clinic

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After opening a pouch of AG1 powder, it should be refrigerated to preserve the integrity and efficacy of the probiotics within the mixture