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As body fat decreases, testosterone rises, estrogen falls, insulin sensitivity improves, and endothelial function recovers

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What is GLP-1 and how does it help with weight loss

We found here that agonist trafficking properties, as well as insulin secretion, mirrored -arrestin recruitment propensity, contrasting with some 14,33 (but not all 34 ) previous work suggesting that -arrestins do not impact GLP-1R trafficking 14,34,35 , as well as reports of coupling of GLP-1R to insulin secretion via -arrestin-1 14 (although not -arrestin-2 60 )