Schedule: Daily subcutaneous injections for 812 weeks, optionally extended to ~16 weeks for longer research goals
So the practical takeaway is not oral is better or SC is better. It is: pick one route, follow the documented per-dose figure for the vial you have, and keep the route constant so that whatever you observe is not confounded by a mid-stream route change
intramuscular hydroxocobalamin This bypasses the possibility of the debate about whether the treatment will be adequately taken, absorbed, and metabolized
Nausea (most common, especially during first 1 to 2 weeks of a new dose) Diarrhea or, just as often, constipation Vomiting (less common but more likely at 9 to 12 mg) Reduced appetite, food noise quieting down (this is the goal, not a side effect) Skin sensitivity (dysesthesia): tingling, prickly feeling, or sunburn-like skin
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