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If you are like millions of Americans who are overweight, you have probably tried everything from dieting to exercise to lose those extra pounds often to no avail

M.MarcheggianiF.CirilliI.et al (2020)

Having a BMI of 27 or above while also having a coinciding weight-related medical condition

Along with preclinical data indicating that long-acting GIPR agonists act in the brain to decrease body weight and food intake via GIPR signalling in inhibitory -aminobutyric acid-producing (GABAergic) neurons 5,6,7 , and by mitigating the emetic effects of GLP-1R agonism 8,9 , GIPRGLP-1R co-agonism has been established as a highly effective strategy for the management of obesity, type 2 diabetes and MASH

While semaglutide pills (under the brand name Rybelsus) are available for type 2 diabetes, as of early 2024, there is no FDA-approved pill version of Wegovy specifically for weight management