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However, recent evidence suggests that the GH produced locally by the colon tumor cells, and not pituitary GH, acts in an autocrine and paracrine manner to suppress the tumor suppressor proteins and to increase nuclear -catenin accumulation and epithelialmesenchymal transition potentially participating in tumor progression (46,47)

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Free radical biology & medicine 49 , 14061416, doi: 10.1016/j.freeradbiomed.2010.07.026 (2010)

Prostaglandins cause inflammation via vasodilation, vascular permeability, and more immune cells to become attracted to fight the infection