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In addition, the medians and 2.5th97.5th percentiles of the results from bootstrap (Simulation, n = 1,000) were used to compare with final model parameters

In this context, Figure 1 illustrates how GLP-1 RAs activate the GLP-1R, subsequently initiating key intracellular signaling pathways such as Epac/PI3K/Akt, cAMP/PKA, and ERK/MAPK

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