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More recently, a link to the gut microbiome and consequential inflammation also has been recognized as contributory factors to these neurodegenerative diseases ( In sum, AD, PD, LBD, and vitiligo are all linked with a loss of melanin and gut dysbiosis ( The purpose of this paper is to provide evidence from the scientific literature of a link between an alteration in melanin levels and disease and to attempt to explain how the alterations could occur and their effects on disease as well as melanins possible role as a storage molecule for energy used by cells to fuel the immune system and for other biological functions

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Feldman et al., 2024