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Participants also showed reduced waist circumference and liver fat content, two critical indicators of metabolic health improvement

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Given that obesity in adolescence is already associated with an increased risk of depression and suicidal ideation, and considering the rise in GLP-1 receptor agonist prescriptions since FDA approval in 2020, it was crucial to investigate whether this treatment impacts psychiatric outcomes

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However, these results differ from previous results, which revealed that oral L-carnitine supplementation had no effect on weight loss during calorie restriction in impaired glucose metabolic patients [31] and during aerobic training in obese women [32]