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Yes, alternative options include lifestyle-based weight management strategies, such as dietary changes, exercise, and supplements
The same goes for suggested risks, some of which make clear sense (eg, more nausea and vomiting) and have been seen in trials, but many others have not, and findings could simply reflect unmeasured confounding. He added: Fortunately, large scale randomised trials with GLP-1RA-based therapies that yield greater weight loss are ongoing and several will report out in the next 1-4 years
This reduced movement allows bile cholesterol to concentrate, a condition called biliary stasis
The four-week titration between dose increases was specifically designed to minimize these effects by allowing GI adaptation before increasing the dose further
Cons: Can develop scar tissue with over-use
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