Pernicious anaemia , an autoimmune condition affecting intrinsic factor production in the stomach, represents the most common indication
For patients with T2DM who are planned to initiate GLP-1 RA therapy, particularly those already at risk of early cardiac autonomic neuropathy (e.g., elevated resting heart rate, borderline reduction in heart rate variability), incorporating an SGLT2i (such as dapagliflozin) in advance or as part of the combination regimen may be a strategy associated with better preservation of cardiac autonomic stability
Discussion The present study showed that 3MST produces persulfurated species such as Cys-SSH and GSSH together with H 2 S 2 and H 2 S 3 as signaling molecules, and increases the levels of persulfurated proteins in a similar manner (Figs 1, 37, and Supplementary Figs S4 and S5) 14, 26, 40
10.1093/jnci/92.12.977 [DOI] [PubMed] [Google Scholar] Weisbord S
However, the slowed gastric emptying effect still applies, so the timing principle holds
