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Beyond cell models, utilizing an organ-on-a-chip model, which is a microfluidic cell culture device that replicates the structure and function of a specific human organ or tissue, may allow researchers to study organ-level responses to drugs, phytonutrients, or synergistic combinations of nutrients in a controlled environment (111113)

Environ Toxicol Chem 25:7286 McKim JM, Nichols JW (1994) Use of physiologically based toxicokinetic models in a mechanistic approach to aquatic toxicology

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Mold exposure and mycotoxin sensitivity vary dramatically between individuals based on genetics, immune status, and detoxification capacity