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Journal of Agricultural and Food Chemistry, 63 (14), 3752-3756

Maintenance and prevention protocol Lower-dose combination approaches support ongoing tissue health and injury prevention in active individuals with chronic tissue demands

The theoretical rationale for combining these peptides is soundthey work through complementary mechanismsbut actual safety and efficacy data for this specific combination does not yet exist in published literature

These two pathways cooperate in several ways: IFN-I generated by cGAS-STING heightens NLRP3 sensitivity, and NLRP3-dependent IL-1 upregulates cGAS via NF-KB, creating a positive-feedback loop

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