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Diagnosis of inborn errors of metabolism from blood spots by acylcarnitines and amino acids profiling using automated electrospray tandem mass spectrometry

Notably, LMF-induced calcium influx through voltage-gated channels may act as a trigger for EV biogenesis and cargo sorting, as calcium signaling is known to regulate vesicle trafficking and the matrix metalloproteinase (MMP) activation [59-61] [Figure 1]