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A small study of 17 male participants showed that eating fruit, such as an apple, before a meal can reduce caloric intake by 18.5%

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2 Methods 2.1 Cell culture DMEM medium (Gibco, USA) supplemented with 10% fetal bovine serum (FBS) (Gibco, USA) and 1% penicillin-streptomycin mixture was used

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