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13a, Supplementary Table 9), suggesting that the distinct rotamer orientation of H296 ECL2 in Cagri-bound CTR (to accommodate the Glu linker) and/or the observed more open ECL3 conformation induced by the lipidated peptide may facilitate or stabilize an active CTR conformation (Supplementary Fig

125 The expression and activity of the SOP enzymes appear to be strongly related to the H 2 S levels to which the corresponding cells or tissues are exposed

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