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Nausea, vomiting, flatulence (gas), and indigestion also occur in many patients

The organ damages following hyperglycemia/ROS stress can be hindered by initiating good glycemic control very early, but is not easily reversed if poorly handled over a longer time period 19

When the N -protecting group was replaced by other aliphatic amides such as cyclopropanecarbonyl and propionyl groups, the reactions proceeded smoothly to afford desired products 5e and 5f in 45 and 80% yield, respectively

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