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The study did, however, also highlighted several negative side effects, including constipation (118 occurrences), diarrhea (100 events), and abdominal pain (41 events per 1,000) ( Abdominal pain, nausea, vomiting, and diarrhea are among the gastrointestinal adverse effects linked to GLP-1 RAs

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Conversely, injecting when dehydrated increases blood viscosity and vascular fragilityadequate hydration 1-2 hours before injection supports vascular stability