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The most commonly reported psychological symptoms include: Mood changes and irritability Some patients describe feeling more emotionally labile, experiencing mood swings, or becoming more easily frustrated during treatment Anxiety symptoms Reports of increased worry, restlessness, or generalised anxiety have been documented, though these may also relate to lifestyle changes or pre-existing tendencies Depressive symptoms A subset of patients report low mood, loss of interest in activities, or feelings of sadness Suicidal ideation Rare reports of suicidal thoughts have been investigated by regulatory authorities, though no causal relationship has been established In the pivotal STEP clinical trial programme for Wegovy, psychiatric adverse events were generally low and similar between the semaglutide and placebo groups

During very active days I have permitted myself to eat up to 750 calories in a single meal

Each hour at room temperature is documented to reduce potency

Are there any risks

BMC Cancer 18 , 306 (2018)