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A study (98) demonstrated that GGT1 and GGT7 stimulate induction of ER stress-related protein, CHOP-10 and immunoglobulin heavy chain binding protein BiP, indicating specific roles for these GGT protein subtypes in ER stress response

a, Audhya, T., Kern, J

This process is closely associated with ROS production induced by iron overload and p53 acetylation (Stockwell et al., 2017)

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