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As a result, exogenous L-citrulline supplementation represents an alternative to increase the amount of L-arginine provided to NOS

Its primary biological directive is to protect delicate cellular architecture, including mitochondrial DNA and cell membranes, from the destructive forces of oxidative stress

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doi: 10.1002/iub.189

Abstract Treatment with glucagon-like peptide-1 receptor agonists (GLP1-RA) in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD) may attenuate kidney disease progression and cardiovascular events but their real-world impact on healthcare utilization and mortality in this population are not well-defined