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Note: Human studies on berberine and gut bacteria are limited

Maintaining hydration, practicing sleep hygiene, and timing over-the-counter analgesics around injection days can ease discomfort

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Pharmacological treatment options include statins as a first-line therapy, with ezetimibe and Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) inhibitors as add-on therapy options in case of persistent dyslipidemia