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S., Kastan, B., Rice, S

The catabolic transsulfuration pathway converts homocysteine to cysteine via two vitamin B 6 -dependent enzymes: cystathionine synthase catalyzes the condensation of homocysteine with serine to form cystathionine, and cystathionine lyase converts cystathionine to cysteine, -ketobutyrate, and ammonia

While some anti-inflammatory drugs associated with classical mechanismssuch as the inhibition of cyclooxygenases (aspirin)are listed as drugs to treat epilepsy, their modest effects are over-shadowed by a new generation of anti-inflammatory/anti-epileptic therapeutic options (see Table 1)

ClinicalTrials.gov was queried to identify registered or ongoing trials

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