Acknowledgements The authors are supported by National Institute of Diabetes and Digestive and Kidney Disease grants R01DK61931 and R01DK68271 (J.R.T.), U.S
Patients were treated with 16 weeks and magnetic resonance imaging (MRI)-proton density fat fraction [MRI-PDFF] and homeostasis model assessment of insulin resistance [HOMA-IR]) and homeostasis model assessment of insulin resistance (HOMA-IR) fibro-inflammation markers (alanine aminotransferase [ALT], corrected T1 [cT1], keratin-18 [K-18] M65, and N-terminal type III collagen pro-peptide [Pro-C3]) was applied
That body of work is genuinely substantial and consistent in the directions it points, spanning tendon, ligament, muscle, gastrointestinal, and nerve-injury models
A person weighing 200 pounds generally has a higher metabolic demand than someone weighing 120 pounds
Bottom line Peptides like insulin and GLP-1s have been lifesaving