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GLP-1RA intervention was associated with a reduction in body weight when compared to those given metformin or placebo (MD = 3.57

Legal status varies by jurisdiction, and researchers should understand the regulatory framework in their location before acquiring either compound

Injectable liraglutide is FDA-approved for different conditions under different brand names with different dosage strengths: is approved for weight management

Artemisinin and its derivatives can induce Ferroptosis by increasing reactive oxygen species

Statistical analyses As Pearson correlation coefficients between the nine metabolite concentration values (three metabolites in three voxels) were substantial even after adjustment for potential confounders, we used principal component analysis (PCA) to identify latent metabolite variables, and extracted scores for each component (see Results and SA7 for details)