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The complex changes in gut bacterial distribution following liraglutide and GUB09-145 treatment is further underscored by drug treatment effects on bacterial species not regulated in DIO mice per se , including increased abundance of Firmicutes ( Clostridium ) and Proteobacteria ( Desulfovibrionaceae ) members

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Food intake returned to baseline between weeks 4 and 5 and increased above baseline for the remainder of the study, including the weeks following treatment cessation