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For isotype control, a consecutive heart section was treated similarly except that the primary MC5-R antibody was replaced by purified normal rabbit IgG (Novus Biologicals, Littleton, CO, USA, # NB810-56910)
GLP-1s are powerful tools, but they dont guarantee success alone
* P 0.05, *** P 0.001, and **** P 0.0001 by 2-way ANOVA followed by Tukey post hoc-tests ( A E and G J ) or multiple unpaired t tests ( F )
For appropriately screened patients under medical supervision, Mounjaro has a well-studied safety profile, though it carries known risks that should be discussed with your doctor
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