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Additionally, the JanusMatrix (human homology) analysis of the impurity sequences resulted in scores ranging from 1.42 (potentially immunogenic) to 5.25 (potentially tolerated or tolerogenic)

Comment: A few commenters did not support the proposal requiring clinicians, once selected for ASM, to remain ASM participants for the entire duration of the model

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Occasional mild injection-site reactions (transient redness or stinging) may occur with subcutaneous administration

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