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Specifically, the effect allele encodes for leucine, which is more hydrophobic than the reference proline allele and may therefore increase stability of the hydrophobic region of the signal peptide (Supplementary Information)

Os animais foram sacrificados aps o tratamento

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these include their overall good safety profile and tolerability, as well as their efficacy in improving glycaemic control, but also, potentially, a small increased risk of acute pancreatitis

This level should be closely monitored by a veterinarian