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doi:10.1152/ajprenal.00729.2010 217

Real-world versus clinical trial timelines Clinical trials represent controlled conditions

Large-scale trials have not shown increased rates of thrombotic events compared to placebo, and the FDA prescribing information does not list blood clots as a recognized adverse effect

Still, many decision-makers want more data before fully embracing coverageand until then, many patients are left paying out of pocket or turning to alternative options