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The chronic inflammatory response in the brain and levels of pro-inflammatory cytokines was improved by DA4-JC, more than by liraglutide (Figure 5 for details of this study)

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Effect of Liraglutide, a Glucagon-Like Peptide-1 Analogue, on Left Ventricular Function in Stable Chronic Heart Failure Patients With and Without Diabetes (LIVE)-A Multicentre, Double-Blind, Randomised, Placebo-Controlled Trial

natriuretic effect via Na + /H + exchanger 3, angiotensin II, inflammation and oxidative stress), although their clinical relevance in patients treated with multiple other agents that also target similar usual suspect pathways is unclear [8387]

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