People who experience anhedonia lose interest in almost all activities, even ones they used to enjoy
You may notice these changes before the number on the scale drops significantly, because fat loss and muscle maintenance can sometimes balance each other out on the scale
Gut bacteria composition influences drug effectiveness and side effect profiles
Consider contacting your GP if: Hair loss is significant, rapid, or causing distress You have noticed other new symptoms alongside hair loss for example, fatigue, weight changes, or cold intolerance (which may suggest a thyroid problem), or nail changes and eyebrow or eyelash loss Hair loss began within weeks to months of starting a new medication You have a personal or family history of autoimmune conditions You notice scalp pain, burning, redness, scaling, pustules, or any signs of scarring these may indicate a more serious condition requiring prompt assessment A child develops patchy hair loss with scaling or broken hairs, which may suggest tinea capitis (a fungal scalp infection) Your GP may recommend blood tests to check thyroid function, full blood count, ferritin, and other relevant markers, in line with NICE CKS guidance on alopecia assessment

A study has shown that decreased uptake of 5-HT was linked to the deletion of a base fragment, especially in IBS-D patients (Pata et al., 2002