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Cardiometabolic benefits and risks of sodium-glucose co-transporter-2 (SGLT-2) inhibitor and glucagon-like peptide-1 (GLP-1) receptor agonist combination therapy in type 2 diabetes: a systematic review

This means refrigerated semaglutide delivers predictable blood glucose suppression and appetite regulation, while improperly stored doses may lose 1030% of their therapeutic potency before injection

Kidney problems : GLP-1 drugs can contribute to kidney failure or exacerbate pre-existing kidney conditions

[1] [2] This expiration date applies when the medication has been continuously refrigerated at the appropriate temperature range and has never been frozen

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