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Symptoms of Pancreatic Cancer According to the Mayo Clinic, symptoms of pancreatic cancer may include: Belly pain that spreads to the sides or back Loss of appetite Weight loss Jaundice, a yellowing of the skin and/or whites of the eyes Light-colored or floating stools Dark-colored urine Itching Newly diagnosed diabetes, or diabetes thats getting harder to control Pain and swelling in an arm or leg, potentially caused by a blood clot Tiredness, weakness, and fatigue IMPORTANT: If you have experienced any of these symptoms, or are concerned you may have pancreatic cancer, seek immediate medical attention