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In theory, this could support tissue repair, but it might also create risks if misregulated particularly in women with clotting disorders or cardiovascular history

The samples were amplified, hybridized onto the array, and subsequently stained

Note that sonication can cause solution warming and potential degradation

The commenter expressed concerns that applying these measures to all heart failure patients could increase reporting burden, while limiting them to attributed patients may result in issues with sample size and representativeness

At higher doses, smaller vials empty too quickly, requiring frequent reconstitution events that introduce contamination risk and inconvenience