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## What You Need Before Starting Gather everything before you begin -- you do not want to pause mid-process with an open vial

12 weeks: 2 vials use 6 mL

Vitamin B12 injections are medically necessary for patients with pernicious anemia, severe malabsorption syndromes, post-bariatric surgery absorption failure, or critically low B12 levels with neurological symptoms

Acknowledgements The authors gratefully acknowledge the participation of the patients and the contribution of the investigators from five hospitals

For a bigger-picture overview of where berberine sits in the metabolic conversation, read about natural alternatives to metformin