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It was demonstrated that the Col I, Col III and TGF-1 protein expression levels, and the CVF, were higher in the rats with MI compared with those who underwent the sham operation (Fig

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197 It strengthens intestinal barrier integrity, regulates microbial metabolic activity, suppresses LPS-TLR4-mediated pro-inflammatory signaling, and coordinates FXR- and TGR5-dependent metabolicinflammatory pathways, forming a protective network across metabolic, immune, and barrier functions