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Combining GLP-1 receptor agonists with lipase inhibitors for enhanced weight management: A review

Despite the fact that both GIP and GLP-1 levels depend on renal metabolism, and are increased in individuals with CKD and renal failure [45, 46], no relevant effects of eGFR on drug exposure were detected when assessing the pharmacokinetics of tirzepatide 5 mg in individuals with preserved renal function or various degrees of renal impairment [47]

The main perioperative concern is pulmonary aspiration during general anaesthesia when protective airway reflexes are suppressed

If you are taking oral HRT with a GLP-1 and nobody adjusted your delivery method, you could be getting significantly less hormone than you think